February 15, 2010
Causes of Liver Cirrhosis Mnemonic
A - Alfa 1 antitrypsin deficiency
B - Budd Chiary Syndrome - Hepatitis B Virus - Biliary cirrhosis - Bilharzia
C - Hepatitis C Virus - Cystic fibrosis - copper overload
D - Drugs
E - Ethanol
F - Fe overload
G - Glycogen storage disease
and while we are at it, lets review the complications:
- Bruising and bleeding due to decreased production of coagulation factors.
- Jaundice due to decreased processing of bilirubin.
- Itching (pruritus) due to bile salts products deposited in the skin.
- Hepatic encephalopathy.
- Sensitivity to medication due to decreased metabolism of the active compounds.
- Hepatocellular carcinoma
- Portal hypertension
- Esophageal varices
- Immune system dysfunction, leading to infection.
- Hepatorenal syndrome - insufficient blood supply to the kidneys, causing acute renal failure.
- Hepatopulmonary syndrome, leading to cyanosis and dyspnea (shortness of breath), characteristically worse on sitting up.